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Dr. Rhonda Patrick’s Multivitamin Alternatives

Dr. Rhonda Patrick’s Multivitamin Alternatives

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Dr. Rhonda Patrick’s multivitamin of choice is called Pure Encapsulations O.N.E. It’s a supplement that is easy to get hold of in the USA, and for some reason, quite difficult outside of the USA.

She has only publicly discussed using one other multivitamin; and that’s Thorne Prenatal, which she used during her pregnancy, and is designed for expecting mothers.

In this post, I’d like to discuss a number of alternatives that contain very similar ingredients to Pure Encapsulations O.N.E.– such that hopefully, you can find these in your home country. Whether its the UK, Canada, Australia, or elsewhere.

In order to accurately compare supplements, I created a spreadsheet that lists all the ingredients of Pure Encapsulations O.N.E., then I compared the ingredients of others until I came up with a list of products that are very similar. You can view the spreadsheet here.

Warnings (don’t make the mistakes I did!)

  • I tried buying supplements from iHerb, and whilst they had a good selection, the import fees to the UK were super expensive! Unless you’re 100% confident the import fees in your country are low, avoid at all costs buying from foreign stores. Unfortunately, a lot of foreign stores hide/make it difficult to ascertain the fact that they’re shipping from outside your country, so be alert.
  • In particular, have noticed a lot of Canadian Amazon sellers ship from the USA. That could be easily overlooked! When buying on Amazon, click the link that says 1 new from (it may say a number other than 1, but that was just an example) – and check the table which shows who the sellers are and which geographical locations they are shipping from.
  • As part of my research, I came across another supplement by Pure Encapsulations called All-In-One. However, sadly, this multivitamin was not cut from the same cloth as O.N.E. and misses off a lot of the essential micronutrients that O.N.E has. Despite it having the same manufacturer.

Thorne Research – Basic Nutrients 2 / Day

Image of bottle of Thorne Research Basic Nutrients. Image of supplement facts from bottle of Thorne vitamins.


Availability: Thorne

Thorne Research brand is Dr. Rhonda Patrick’s favorite choice of supplements. She currently uses it for her magnesium citramate, vitamin D3, Meriva, and more.

This particular supplement is very nutritionally diverse and provides a good alternative to O.N.E. It contains folate as opposed to folic acid.


  • Noticeably it doesn’t contain Iron or Potassium. However, for red meat eaters, the former may be acceptable.
  • It’s not cheap, coming in around $30 for a 1 month supply (each pack contains 60 capsules, and a daily serving is 2)

Now Foods Special Two

Image of bottle of Now Special Two multivitamin.Image of supplement facts of Now Foods multivitamin.


Availability: Amazon USA

Now is a reputable brand that Rhonda has discussed using (for other products) in the past.  This particular multivitamin by now covers a very broad spectrum of the essential micronutrients our body needs. Each serving is 4 pills, and a 120 capsule tub contains 30 days of servings.

It actually has the broadest coverage of any of the multivitamins I’ve compared. It even has copper, which O.N.E misses off (not sure why!)

In addition to the essential micronutrients, they have also included some popular plant and herb extracts, such as spirulina, chlorella, green tea extract, etc.


  • Contains Folic acid rather than folate. A negative for those with the MTHFR polymorphism that leads to poor processing of folic acid (~60% of the population).
  • A potential negative is that it contains so many “extra” things on top of the micronutrients, purists (like myself) may prefer it just sticks to vitamins & minerals.
  • Reasonably high monthly cost – each tub is about $30 and lasts a month (although that is $1 a day, so not crazy!)

Honorable Mention

Optimum Nutrition – Opti-Men

Availability: Amazon USA 

Image of Optimum Nutrition bottle of Opti-Men. Image of Supplement Facts of bottle of Optimum Nutrition Opti-Men.

  • Comprehensive micronutrient coverage
  • Generally, a well-known brand so should be available in many locations
  • Contains folic acid instead of folate
  • Includes a lot of additional herbs & plants, that may or may not be desirable

If you liked this article please visit this other article about Dr. Rhonda Patrick’s recommendations on supplements:

Dr. Rhonda Patrick’s Supplements

If you want to learn about supplements other than those on Dr. Rhonda Patrick’s recommended list, then visit this article as well:

Tim Ferris Supplements

If you want to see more Top Supplements from Thorne, visit our article on their offerings:

Thorne’s Top Products

Illia Sheremet

Thursday 1st of March 2018

Thanks a lot for the article!


Wednesday 20th of December 2017

What do you think about Adam & Eve from Now Foods?